Nucala: how long were the pivotal tox studies?

“In toxicology studies up to 6 months duration, no target organs of toxicity were identified at a SC dose of 10 mg/kg or intravenous (IV) doses of 10-100 mg/kg administered once every 4 weeks for a total of 7 doses.”

“In a 6-month toxicology study, Cynomolgus monkeys received mepolizumab (SB240563) at a subcutaneous dose of 10 mg/kg or an intravenous dose of 10 or 100 mg/kg once every 4 weeks for a total of 7 doses”

“In a 6-month toxicology study, Cynomolgus monkeys received mepolizumab (SB240563) at a subcutaneous dose of 10 mg/kg or an intravenous dose of 10 or 100 mg/kg once every 4 weeks for a total of 7 doses”