Ilumya: how long were the pivotal tox studies?

“Toxicity of tildrakizumab was evaluated in repeated dose studies of 3-months and 9 months treatment duration.”

“In the 3-months study, the NOAEL was 140 mg/kg following either IV or SC administration every 2 weeks; in the 9-months study, the NOAEL was 100 mg/kg SC Q2W.”

“In the 3-months study, the NOAEL was 140 mg/kg following either IV or SC administration every 2 weeks; in the 9-months study, the NOAEL was 100 mg/kg SC Q2W.”