Aimovig: how long were the pivotal tox studies?

“In the pivotal 3- and 6-month toxicity study with 15-week recovery period, SC doses of 0, 25, and 150 mg/kg were administered 2x per week (4/sex/group).”

“the pivotal (1- mo/acute IV + 4-month recovery; combined 3- and 6-month; enhanced pre- and postnatal development [ePPND]) studies were adequate by design and conduct”

“SC doses of 0, 25, 75, 100, and 225 mg/kg were administered 2x per week or a single IV dose of 0 or 100 mg/kg was administered”