Actemra tocilizumab · IL-6R Monkey surrogate 26 wk Conducted Not conducted Conducted Not conducted →
Adakveo crizanlizumab · P-selectin Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Adbry tralokinumab · IL-13 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Aduhelm aducanumab · Aggregated amyloid-β Monkey Rat Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Aimovig erenumab · CGRP receptor Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Ajovy fremanezumab · CGRP Monkey Rat 26 wk Not conducted Not conducted Conducted Not conducted →
Alhemo concizumab · TFPI Monkey Rabbit 52 wk Not conducted Not conducted Conducted Not conducted →
Andembry garadacimab · Factor XIIa Monkey Mouse 26 wk Not conducted Not conducted Conducted Not conducted →
Anthim obiltoxaximab · B. anthracis PA Monkey Rat 1 wk Not conducted Not conducted Conducted Partial / alternative →
Arzerra ofatumumab · CD20 Monkey 30 wk Not conducted Not conducted Conducted Not conducted →
Avastin bevacizumab · VEGF-A Monkey Rabbit 26 wk Not conducted Not conducted Conducted Not conducted →
Bavencio avelumab · PD-L1 Monkey 13 wk Not conducted Not conducted Not conducted Not conducted →
Benlysta belimumab · BLyS (BAFF) Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Beovu brolucizumab · VEGF-A Monkey n/a Not conducted Not conducted Conducted Not conducted →
Beyfortus nirsevimab · RSV F protein Monkey 4 wk Not conducted Not conducted Not conducted Not conducted →
Bimzelx bimekizumab · IL-17A/IL-17F Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Briumvi ublituximab · CD20 Monkey surrogate 26 wk Conducted Not conducted Conducted Not conducted →
Cablivi caplacizumab · von Willebrand factor (A1 domain) Monkey Pig Other 26 wk Not conducted Not conducted Conducted Not conducted →
Campath alemtuzumab · CD52 Monkey Mouse surrogate 4 wk Not conducted Not conducted Conducted Not conducted →
Cimzia certolizumab pegol · TNF-α Monkey surrogate 52 wk Conducted Not conducted Conducted Not conducted →
Cinqair reslizumab · IL-5 Monkey Mouse 26 wk Conducted Conducted Conducted Partial / alternative →
Cosentyx secukinumab · IL-17A Monkey surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Crysvita burosumab · FGF23 Monkey Rabbit surrogate 40 wk Not conducted Not conducted Conducted Not conducted →
Cyramza ramucirumab · VEGFR2 Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Danyelza naxitamab · GD2 Rat 13 wk Not conducted Not conducted Not conducted Partial / alternative →
Darzalex daratumumab · CD38 Monkey surrogate 6 wk Not conducted Not conducted Not conducted Not conducted →
Dupixent dupilumab · IL-4Ra Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Ebanga ansuvimab · Zaire ebolavirus glycoprotein Monkey 4 wk Not conducted Not conducted Not conducted Not conducted →
Ebglyss lebrikizumab · IL-13 Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Emgality galcanezumab · CGRP Monkey Rat 26 wk Not conducted Not conducted Conducted Not conducted →
Empliciti elotuzumab · SLAMF7 no relevant sp. Monkey none Not conducted Not conducted Not conducted Not conducted →
Enflonsia clesrovimab · RSV F protein (site IV) Rat 2 wk Not conducted Not conducted Conducted Not conducted →
Enjaymo sutimlimab · Complement C1s Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Enspryng satralizumab · IL-6R Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Entyvio vedolizumab · α4β7-integrin Monkey Rabbit 26 wk Not conducted Not conducted Conducted Not conducted →
Erbitux cetuximab · EGFR Monkey Rat 39 wk Conducted Not conducted Conducted Not conducted →
Evenity romosozumab · Sclerostin Monkey Rat 26 wk Not conducted Conducted Conducted Not conducted →
Evkeeza evinacumab · ANGPTL3 Monkey Rat Rabbit 26 wk Not conducted Not conducted Conducted Not conducted →
Exdensur depemokimab · IL-5 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Fasenra benralizumab · IL-5Rα Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Gamifant emapalumab · IFN-γ Monkey surrogate 13 wk Not conducted Not conducted Conducted Not conducted →
Gazyva obinutuzumab · CD20 Monkey 26 wk Not conducted Not conducted Partial / alternative Not conducted →
Herceptin trastuzumab · HER2 Monkey surrogate 26 wk Conducted Not conducted Conducted Not conducted →
Humira adalimumab · TNF-α Monkey 39 wk Partial / alternative Not conducted Conducted Not conducted →
Hympavzi marstacimab · TFPI Monkey Rat 26 wk Not conducted Not conducted Conducted Not conducted →
Ilaris canakinumab · IL-1β Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Ilumya tildrakizumab · IL-23 p19 Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Imaavy nipocalimab · FcRn Monkey 26 wk Not conducted Not conducted Conducted Partial / alternative →
Imfinzi durvalumab · PD-L1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Imjudo tremelimumab · CTLA-4 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Jemperli dostarlimab · PD-1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Kevzara sarilumab · IL-6R Monkey surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Keytruda pembrolizumab · PD-1 Monkey 26 wk Not conducted Not conducted Not conducted Not conducted →
Kisunla donanemab · Amyloid-β (N3pG) Monkey Mouse surrogate 22 wk Not conducted Not conducted Not conducted Not conducted →
Lartruvo olaratumab · PDGFRα Monkey surrogate 39 wk Not conducted Not conducted Partial / alternative Not conducted →
Leqembi lecanemab · Amyloid-β protofibrils Monkey surrogate 39 wk Not conducted Not conducted Not conducted Not conducted →
Libtayo cemiplimab · PD-1 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Loqtorzi toripalimab · PD-1 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Lucentis ranibizumab · VEGF-A Monkey Rabbit 26 wk Not conducted Not conducted Conducted Not conducted →
Margenza margetuximab · HER2 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Monjuvi tafasitamab · CD19 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Nemluvio nemolizumab · IL-31RA Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Niktimvo axatilimab · CSF-1R Monkey surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Nucala mepolizumab · IL-5 Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Ocrevus ocrelizumab · CD20 Monkey 24 wk Not conducted Not conducted Conducted Not conducted →
Omvoh mirikizumab · IL-23 p19 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Opdivo nivolumab · PD-1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Pasatru garetosmab · Activin A Monkey Rat 26 wk Conducted Not conducted Conducted Not conducted →
Penpulimab penpulimab · PD-1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Perjeta pertuzumab · HER2 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Piasky crovalimab · Complement C5 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Portrazza necitumumab · EGFR Monkey surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Poteligeo mogamulizumab · CCR4 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Praluent alirocumab · PCSK9 Monkey Rat 26 wk Not conducted Conducted Conducted Not conducted →
Praxbind idarucizumab · Dabigatran Monkey Rat 4 wk Not conducted Not conducted Conducted Not conducted →
Prolia denosumab · RANKL Monkey surrogate 52 wk Not conducted Not conducted Conducted Not conducted →
Raxibacumab raxibacumab · B. anthracis protective antigen Monkey Rabbit 3 wk Not conducted Not conducted Partial / alternative Not conducted →
Remicade infliximab · TNF-α Monkey Mouse surrogate 26 wk Conducted Not conducted Conducted Not conducted →
Repatha evolocumab · PCSK9 Monkey 26 wk Not conducted Conducted Conducted Not conducted →
Rituxan rituximab · CD20 Monkey 8 wk Not conducted Not conducted Conducted Partial / alternative →
Rystiggo rozanolixizumab · FcRn Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Saphnelo anifrolumab · IFNAR1 Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Sarclisa isatuximab · CD38 Monkey 3 wk Not conducted Not conducted Conducted Conducted →
Siliq brodalumab · IL-17RA Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Simponi golimumab · TNF-α Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Simulect basiliximab · IL-2Rα (CD25) Monkey 4 wk Conducted Not conducted Partial / alternative Not conducted →
Skyrizi risankizumab · IL-23 p19 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Soliris eculizumab · Complement C5 Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Spevigo spesolimab · IL-36R Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Stelara ustekinumab · IL-12/23 p40 Monkey surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Sylvant siltuximab · IL-6 Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Synagis palivizumab · RSV F protein no relevant sp. Monkey Rat none Not conducted Not conducted Not conducted Not conducted →
Takhzyro lanadelumab · Plasma kallikrein Monkey Rat 26 wk Not conducted Not conducted Conducted Not conducted →
Taltz ixekizumab · IL-17A Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Tecentriq atezolizumab · PD-L1 Monkey Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Tepezza teprotumumab · IGF-1R Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Tevimbra tislelizumab · PD-1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Tezspire tezepelumab · TSLP Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Tremfya guselkumab · IL-23 p19 Monkey 24 wk Not conducted Not conducted Conducted Not conducted →
Trogarzo ibalizumab · CD4 Monkey 39 wk Not conducted Not conducted Partial / alternative Not conducted →
Tysabri natalizumab · α4-integrin Monkey Pig Other 26 wk Conducted Conducted Conducted Not conducted →
Tzield teplizumab · CD3 Monkey Mouse surrogate 1 wk Not conducted Not conducted Conducted Not conducted →
Ultomiris ravulizumab · Complement C5 Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Unituxin dinutuximab · GD2 Monkey Rat 4 wk Not conducted Not conducted Not conducted Not conducted →
Unloxcyt cosibelimab · PD-L1 Monkey 13 wk Not conducted Not conducted Conducted Not conducted →
Uplizna inebilizumab · CD19 Mouse surrogate 26 wk Not conducted Not conducted Conducted Not conducted →
Vectibix panitumumab · EGFR Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Veopoz pozelimab · Complement C5 Monkey 26 wk Not conducted Not conducted Partial / alternative Not conducted →
Voyxact sibeprenlimab · APRIL Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Vyepti eptinezumab · CGRP Monkey Rat Rabbit 26 wk Not conducted Not conducted Conducted Not conducted →
Vyloy zolbetuximab · Claudin 18.2 Monkey Mouse surrogate 13 wk Not conducted Not conducted Conducted Not conducted →
Xolair omalizumab · IgE Monkey Mouse 26 wk Conducted Not conducted Conducted Not conducted →
Yartemlea narsoplimab · MASP-2 Monkey Mouse 26 wk Not conducted Not conducted Conducted Not conducted →
Yervoy ipilimumab · CTLA-4 Monkey 26 wk Not conducted Not conducted Conducted Not conducted →
Zinbryta daclizumab · IL-2Rα (CD25) Monkey 39 wk Not conducted Not conducted Conducted Not conducted →
Zinplava bezlotoxumab · C. difficile toxin B Mouse 3 wk Not conducted Not conducted Conducted Not conducted →
Zynyz retifanlimab · PD-1 Monkey 13 wk Not conducted Not conducted Not conducted Not conducted →