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Atlas/Antibody-drug conjugates

Antibody-drug conjugates

Antibodies carrying a cytotoxic payload. 14 approved products. Click any cell to read the regulator's sentence.

Check my plan against these
Which species?Monkey + rodent13 of 14 precedents → How long?13 weeksmedian, range 10–26 wk → What did they skip?14 of 14 skipped carcinogenicityGenotox skipped 0/14 · repro 6/14 → How was the first dose set?2 of 14 say2 more partly · 10 not stated publicly →

Longest pivotal study, every precedent

Hover a dot · click to open · striped = derived from dosing schedule
041326 wk
ConductedConductedPartial / alternativePartial / payload / alternativeNot conductedNot conductedNot statedNot stated
14 of 14 shown
Open
Adcetrisbrentuximab vedotin · CD30 →
Besponsainotuzumab ozogamicin · CD22 →
Datrowaydatopotamab deruxtecan · Trop-2 →
Decnupazpivekimab sunirine · CD123 →
Elaheremirvetuximab soravtansine · FRα →
Emrelistelisotuzumab vedotin · c-Met →
Enhertufam-trastuzumab deruxtecan · HER2 →
Kadcylaado-trastuzumab emtansine · HER2 →
Mylotarggemtuzumab ozogamicin · CD33 →
Padcevenfortumab vedotin · Nectin-4 →
Polivypolatuzumab vedotin · CD79b →
Tivdaktisotumab vedotin · Tissue factor →
Trodelvysacituzumab govitecan · Trop-2 →
Zynlontaloncastuximab tesirine · CD19 →