Alhemo: how long were the pivotal tox studies?

“In a 52-week repeat dose toxicity study in sexually mature Cynomolgus monkeys, animals received 0.5, 1 or 9 mg concizumab/kg/day for 52 weeks.”

“In a 26-week repeat dose toxicology study in sexually mature Cynomolgus monkeys, animals were given 0, 3 or 9 mg concizumab/kg/day s.c. or 30 mg/kg/week i.v. with a 13-week recovery period.”

“toxicity studies, concizumab was dosed i.v. once weekly or s.c. once daily.”