Humira: how long were the pivotal tox studies?

“Repeat dose toxicity studies of 4 weeks (32 – 157 mg/kg bw) and 39 weeks (32- 215 mg/kg bw) duration were performed.”

“Repeat dose toxicity studies of 4 weeks (32 – 157 mg/kg bw) and 39 weeks (32- 215 mg/kg bw) duration were performed.”

“Adalimimab was generally administered via the i.v. route, while the intended clinical route is s.c. administration.”