Winlevi: animal efficacy model or human cells?

“In vivo, its efficacy was shown in the hamster flank organ model, where topical application reduced testosterone-induced enlargement without systemic effects.”

“The Golden Syrian Hamster animal model has been extensively used to evaluate anti-seborrheic mechanisms through modulation of sebum production and sebocyte proliferation; this animal model closely replicates the pathogenic mechanism involved in acne.”

“The hamster flank organ acne vulgaris model had been chosen which is acceptable as it composed of clusters of large sebaceous glands.”