Sephience: how long were the pivotal tox studies?

“A 39-week study was performed in marmoset monkeys with a 4-week recovery period.”

“The GLP-compliant studies in rats comprised studies with 2- 13- and 26-weeks of treatment followed by, respectively, 2- , 4- and 4- weeks recovery periods. The studies in marmoset monkeys had treatment durations of 2- 13- and 39-weeks”

“All studies were conducted with administration of sepiapterin once a day by oral gavage”