Fexinidazole: how long were the pivotal tox studies?

“Repeat-dose toxicology studies were conducted in rats and dogs for up to 28 days.”

“The liver and thymus were identified as the target organs of toxicity in repeat-dose toxicity studies in rats and dogs at doses of 50, 200, and 800 mg/kg/day for 28 days.”

“Route of administration: Oral gavage Formulation/vehicle: 5% Tween 80/0.5% Methyl cellulose 400 cP”