Reyvow: how long were the pivotal tox studies?

“In the 39-week study, the high dose was reduced to 40 mg/kg/day because of intolerability.”

“General Toxicology: the oral toxicity of lasmiditan was tested in Sprague-Dawley rat (4-week + 2-week recovery, 13-week + 4-week recovery, and 26-week + 8-week recovery) and Beagle dog (2-week, 4-week + 2-week recovery, 13-week + 4-week recovery, and 39-week + 8-week recovery).”

“All pivotal in vivo nonclinical studies were conducted using oral administration.”