Olinvyk: how long were the pivotal tox studies?

“The nonclinical program supporting clinical development of Oliceridine included a pharmacology, ADME, general toxicology studies (28 days duration in rats and 14 days duration in monkeys), genetic toxicology, and reproductive toxicity studies.”

“The nonclinical program supporting clinical development of Oliceridine included a pharmacology, ADME, general toxicology studies (28 days duration in rats and 14 days duration in monkeys), genetic toxicology, and reproductive toxicity studies.”

“Intravenous bolus administration is the intended clinical route of administration; however, continuous infusion was selected to maximize daily exposure in the toxicology studies.”