Klisyri: how long were the pivotal tox studies?

“Tirbanibulin was evaluated in repeat-dose general toxicity studies involving topical administration to the skin of rats and minipigs for up to 4 weeks, as well as in studies that involved oral dosing of rats and dogs for up to 4 weeks.”

“Tirbanibulin was evaluated in repeat-dose general toxicity studies involving topical administration to the skin of rats and minipigs for up to 4 weeks, as well as in studies that involved oral dosing of rats and dogs for up to 4 weeks.”

“Tirbanibulin has been evaluated in a battery of nonclinical studies that included evaluation of ADME, pharmacology, safety pharmacology, repeat-dose toxicity (via both the oral and topical routes), genetic toxicology, reproductive toxicology, and evaluation for potential to induce ocular irritation or sensitization.”