Nereus: how long were the pivotal tox studies?

“Repeat-dose oral toxicity studies with tradipitant have been conducted in mice (13 weeks), rats (up to 6 months), and dogs (up to 3 months).”

“repeat-dose toxicity studies in mice (13 weeks), Fisher rats (1, 3, and 6 months), Han Wistar rats (3 months), and dogs (1 and 3 months)”

“In a 6-month toxicity study in Fischer 344 rats, tradipitant was orally administered once daily at doses of 0 (vehicle), 15, 150, or 1500 mg/kg/day.”