Inluriyo: which risks did reviewers probe?

“Imlunestrant affected T-cell dependent antibody responses across studies but because animals mounted anti-KLH IgM and IgG responses it was concluded that effects on seroconversion did not functionally suppress the immune response and were considered non-adverse.”

“Concentrations in uveal tract were high through to the end of the study at 672 hours and concentrations seem to be declining only very slowly.”

“The major target organs of toxicity in the general rat and monkey toxicology studies were male and female reproductive organs, hematopoietic/lymphatic system, kidney, urinary bladder, and eye and were generally consistent across the short and long-term studies.”