Breyanzi: how long were the pivotal tox studies?

“periods (0-100 days), in contrast with the control group (died by day 10-11).”

“In this light, traditional toxicity, including single and repeat-dose toxicity, genotoxicity, carcinogenicity, reproductive and developmental toxicity, and local tolerance studies were deemed of negligible utility and thus were not conducted.”

“JCAR017 is an autologous cell-based product administered by intravenous infusion.”