Removab: how long were the pivotal tox studies?

“Repeat-dose toxicity studies have not been submitted.”

“In the few studies performed in rats, mice and one cynomolgus monkey, no acute toxicity was seen even at very high doses of catumaxomab.”

“Administration of 150 µg i.p. catumaxomab showed an histopathological moderate subchronic inflammation of skin and abdominal muscle after administration of the test item in one animal.”