Hemgenix: how long were the pivotal tox studies?

“At 26 weeks following IV administration of 5x1012 to 9x1013 gc/kg HEMGENIX in NHPs, high levels of vector DNA were detected in a dose-dependent manner in the liver.”

“The single IV dose toxicology studies and the analysis of the safety parameters were performed under GLP compliance.”

“IV-route of administration, the clinical route, is used in all toxicological studies.”